Erika Shinohara (Fumi Nikaido) is a first year of high school student. While talking to friends, she makes up a story about her "boyfriend." In reality, Erika Shinohara doesn't have a boyfriend. Erika's friends soon begin to doubt her story and Erika is also running out of lies. Erika then sees a pretty boy on the street and takes his picture discreetly. She later shows his picture to her friends as her boyfriend. The boy in the picture is Kyouya Sata (Kento Yamazaki) and happens to attend the same school as Erika. She tells Kyouya about her situation and asks him to be her pretend boyfriend. Even though Kyouya has a pretty appearance, he has a dark side.
A mysterious creature destroys 70% of the moon. The creature then warns that if he is not destroyed by March of next year, Earth will be next. The creature also demands that he becomes the homeroom teacher for 3rd grade E class at Kunugigaoka Junior High School. The government is powerless to say no.
The creature then becomes the homeroom teacher of 3rd grade E class which consists of failed students including Nagisa Shiota (Ryosuke Yamada). The creature is called Teacher Koro.
Meanwhile, the government requests that the students try to kill Teacher Koro even though he possesses super powers. The government offers a 10 billion yen reward for whomever successfully kills him. The students are confused by the situation, but decide to kill Teacher Koro.
When their class begins with Teacher Koro, the students finds themselves having a good time with their new teacher.
No matter how hard he thinks about it, Todoin Seiya cannot figure out why he doesn’t have a girlfriend in his 16 year lifespan. Physically attractive, naturally smart, athletic and, on top of that, comes from a wealthy and politically significant family. And it’s not like he hasn’t tried either; but every girl he asks out flat out rejects him. Seiya sets a goal for himself to get a girlfriend by the time high school ends and rejection isn’t going to stop him from trying again. But it sure is heartbreaking when you get rejected this many times without knowing why.
Yusuke Serizawa (Keisuke Koide) works at a law office. He gets into a car accident. A woman helps him and she looks familiar to him, but he doesn't remember who she is. Yusuke Serizawa looks back at his past romances.
Makoto (Kyoko Yoshine) transfers to Omotesando High School in Tokyo from Kagawa Prefecture. Makoto was enthusiastic in the chorus back at her old high school and she looks forwards to joining the well-known chorus at Omotesando High School. Additionally, her prior teacher, Ariake Suzuki (Yuu Shirota), is now an advisor of the chorus at Omotesando High School. He taught her the joys of the chorus.
But, the chorus at Omotesando High School is now in decline and is set to be abolished. Makoto decides to rebuild the chorus.
Tsubame Haruna (Suzu Hirose) is a female high school student. She spends her days peaceful, while concerned about other's facial expressions. She is forced to become the student president. Tsubame Haruna then meets Kei Shizukui (Ryunosuke Kamiki). He has a talented speech writer. With his help, Tsubame Haruna starts a revolution at her corrupt school.
Akiyama Shuntaro, a fourth-year university student who has had a good upbringing because his father is a member of the board of a well-known company, Shuntaro’s employment has somehow or other been determined with those connections and he spends his days aimlessly. Even though he questions his present way of life, he has not taken any constructive action. While on the way to uni one day, Shuntaro hits his head inside the train and loses consciousness, now he can see characters showing train station names in commuters’ heads. Then one day, he happens to see a man without a station name appearing above his head.
Yoshikawa Nao stays behind to live by herself when her parents leave to inherit her grandpa's farm in the country. On the day she moves into her new apartment, she discovers that it was rented also to Uehara Hisashi; a cute, super-cool, popular guy from her school. Not only did their housing agency unexpectedly close down, the landlord of the apartment tells them that they had to pay more for their apartment than they had expected. With no money and no home to return to, Nao and Hisashi decide to live together as flatmates.
Sixth grader Ayase Chihaya, a tomboy with no ambitions or goals of her own, gets to know Wataya Arata, a transfer student at Chihaya's elementary school and an outcast. Through Arata, Chihaya picks up karuta and they form a team with their other friend and classmate Mashima Taichi. After graduating elementary school, Chihaya continues to play karuta hoping for a chance to meet Arata again after he went back to Fukui to take care of his sick grandfather. As time passed and Chihaya enters high school, she starts a karuta club with Taichi so that they can finally meet Arata again.