Natsumi Uemura (Erika Toda) is an English teacher at Meiryo High School. She has always dreamed of being a teacher. Until her middle school days Natsumi lived in the U.S. She is now a first grade home room teacher and advisor to the basketball team. She is bright and has a positive character, so she is popular with the students. Shuji Kashiwagi (Haruma Miura) is a biology teacher at the same high school. Shuji is a 2nd grade home room teacher. Shuji is faithful and considerate. He deals with students with his heart so not only students but also their parents support him completely.
Azusa (Anna Ishii) and Narumi (Fuka Koshiba) are 2nd grade high school students. They lack confidence and also any kind of ambitions. Hazuki (Karin Ono), Tamaki (Mika Akizuki) and Mika (Miku Uehara) are also unnoticed students at the same high school. These five girls form a dance club and begin to dance to get credits. They soon learn the joys of dancing and also learn to express themselves.
Takashi Hayama (Nijiro Murakami) is a third year high school student. He falls in love with Azusa Oribe (Akari Hayami) at first sight and they begin to date.
One day, Azusa tells Takashi "people who meet me, forget about me several hours later."
Takashi doesn't believe Azusa, but by chance he realizes that he forgot about Azusa. So he won't forget Azusa, Takashi begins to leave a note for himself and Azusa.
Hatori Matsuzaki (Mirei Kiritani) is a female high school student. She has a crush on her childhood friend Rita Terasaka (Kento Yamazaki) and believes he will eventually choose her as her heroine, but Rita Terasaka begins dating Miho Adachi. Meanwhile, the most popular male student, Kosuke Hiromitsu (Kentaro Sakaguchi) takes an interest in Hatori Matsuzaki.
When she was a middle school student, Futaba Yoshioka liked Kou Tanaka who was unlike the other boys and quite gentle. Kou Tanaka then moved away and they lost contact.
At the end of Futaba Yoshioka's first year as a high school student she meets Kou Tanaka again. Kou Tanaka’s name has changed to Kou Mabuchi and his personality seems different from his middle school days.
Tomomitsu Tsuchiya (Taisuke Fujigaya) is the captain of his high school basketball team. He is also a senior at his school. Even though he is not that good in basketball, he is selected as bench player for the prefecture qualifying round. The underclassmen on his team, who are all better than him, are not happy about his selection.
Tomomitsu Tsuchiya then meets Sae Hatori (Mizuki Yamamoto). She is also a senior at the same high school. She keeps watching Tomomitsu Tsuchiya shoot three pointers. They become closer and develop a romantic relationship. Suddenly, Sae transfers to another school without saying a word.
Naho Takamiya (Tao Tsuchiya) is a 2nd year high school student. During the spring, Naho Takamiya receives a letter sent by herself from 10 years in the future. In the letter, she liked transfer student Kakeru Naruse (Kento Yamazaki). Kakeru Naruse carried emotional scars from his mother's suicide and he died one year later. 26-years-old Naho Takamiya thinks about Kakeru Naruse often.
2nd year high school student Naho Takamiya, with the knowledge of what she feels 10 years in the future, takes action to change her future.
Erika Shinohara (Fumi Nikaido) is a first year of high school student. While talking to friends, she makes up a story about her "boyfriend." In reality, Erika Shinohara doesn't have a boyfriend. Erika's friends soon begin to doubt her story and Erika is also running out of lies. Erika then sees a pretty boy on the street and takes his picture discreetly. She later shows his picture to her friends as her boyfriend. The boy in the picture is Kyouya Sata (Kento Yamazaki) and happens to attend the same school as Erika. She tells Kyouya about her situation and asks him to be her pretend boyfriend. Even though Kyouya has a pretty appearance, he has a dark side.
A mysterious creature destroys 70% of the moon. The creature then warns that if he is not destroyed by March of next year, Earth will be next. The creature also demands that he becomes the homeroom teacher for 3rd grade E class at Kunugigaoka Junior High School. The government is powerless to say no.
The creature then becomes the homeroom teacher of 3rd grade E class which consists of failed students including Nagisa Shiota (Ryosuke Yamada). The creature is called Teacher Koro.
Meanwhile, the government requests that the students try to kill Teacher Koro even though he possesses super powers. The government offers a 10 billion yen reward for whomever successfully kills him. The students are confused by the situation, but decide to kill Teacher Koro.
When their class begins with Teacher Koro, the students finds themselves having a good time with their new teacher.
No matter how hard he thinks about it, Todoin Seiya cannot figure out why he doesn’t have a girlfriend in his 16 year lifespan. Physically attractive, naturally smart, athletic and, on top of that, comes from a wealthy and politically significant family. And it’s not like he hasn’t tried either; but every girl he asks out flat out rejects him. Seiya sets a goal for himself to get a girlfriend by the time high school ends and rejection isn’t going to stop him from trying again. But it sure is heartbreaking when you get rejected this many times without knowing why.